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Glentek/Riluzol (Riluzole)
$1,100.00
Glentek Riluzol (riluzole, tablet form) is a medication used for the treatment of amyotrophic lateral sclerosis (ALS).
What is riluzole?
Riluzole is a glutamate release inhibitor indicated for the treatment of patients with amyotrophic lateral sclerosis (ALS)[1,5]. Glentek (riluzole) is a generic form of Rilutek (riluzole).
It is available as tablets each containing 50mg riluzole.
How does riluzole work?
It is still not clear how ALS develops, however it seems that the neurotransmitter glutamate plays a role in cell death.
Riluzole is thought to act by inhibiting the release of glutamate[1,2,3,4,5].
Riluzole aims to extend life or the time to mechanical ventilation for patients with amyotrophic lateral sclerosis (ALS). There is no evidence that it has a therapeutic effect on motor function, lung function, fasciculations, muscle strength and motor symptoms[2,3,4,5].
Where has riluzole been approved?
Riluzole was approved for the treatment of patients with ALS by:
- Therapeutic Goods Administration (TGA), Australia, February 2016[5]
- The Medicines Evaluation Board (MEB), The Netherlands, June 2014[1].
Please note that this medication may have also been approved in other regions than the ones we’ve listed. If you have a question about its approval in a specific country feel free to contact our support team.
Please be aware that any decision to use a prescription generic or brand name medicine should always be taken in consultation with a medical professional. The FDA has sent warning letters to drugmakers in India and Pakistan concerning the quality of their medicines.
How is riluzole taken?
The standard dosage is[1,5]:
- 1 tablet of 50 mg every 12 hours (total daily dose: 100 mg).
Complete information about how and how much riluzole you need to take can be found in the official prescribing information listed in our references section[1,2,3].
Note: Please consult with your treating doctor for personalised dosing.
Are there any known side effects or adverse reactions of riluzole?
Common adverse reactions
The most common adverse reactions listed in the prescribing information include[1]:
- asthenia (Lack of energy and strength)
- nausea (feeling sick)
- dizziness
- decreased lung function
- abdominal pain
- abnormal liver function tests.
Serious adverse reactions
The serious adverse reactions listed in the prescribing information include[1]:
- liver injury
- neutropenia (low white blood cells count)
- interstitial lung disease.
Use in specific populations
Riluzole can be fatal for a fetus, it is advised to avoid pregnancies and breast feeding[1].
Riluzole should not be used by patients who have liver disease or increased blood levels of some liver enzymes (transaminases)[1].
For a comprehensive list of side effects and adverse reactions please refer to the official prescribing information[1,5].
Tablets | 56 tablets of 50 mg |
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